ABSTRACT

There are several processes by which exercise affects the production of reactive oxygen species (ROS) and nitric oxide (NO). Moreover, the complexity of the association of these issues is accentuated if we consider the specic adjustments caused by physical activity on the different organs and tissues (Kojda and Hambrecht 2005, Powers et al. 2010, Calvert et al. 2011). In this chapter, tissuespecic concerns about NO and ROS during exercise are discussed following a translational view: from the relationship between redox signaling and health promoting effects by chronic exercise to molecular redox targets triggered during acute exercise sessions.