ABSTRACT

As with the two previous editions, Barile’s Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered.

KEY FEATURES

• Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment

• Examines the complex interactions associated with clinical toxicological events

• Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs

• Covers effect of toxins on body systems and drug-induced adverse reactions

• Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students

The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology.

part Section I|1 pages

Introduction to Basic Toxicological Principles

chapter 1|7 pages

Introduction

chapter 5|9 pages

Exposure

chapter 6|11 pages

Effects

chapter 7|8 pages

Dose–Response

chapter 10|28 pages

Toxicokinetics

part Section II|1 pages

Toxicity of Therapeutic Agents

chapter 14|20 pages

Opioids and Related Agents

chapter 15|21 pages

Sympathomimetics

chapter 16|25 pages

Hallucinogenic Agents

chapter 19|12 pages

Anabolic–Androgenic Steroids

chapter 20|17 pages

Cardiovascular Toxicology

chapter 21|11 pages

Antineoplastic Agents

chapter 22|13 pages

Vitamins

chapter 23|16 pages

Herbal Remedies

part Section III|1 pages

Toxicity of Nontherapeutic Agents

chapter 24|19 pages

Alcohols and Aldehydes

chapter 25|19 pages

Gases

chapter 26|38 pages

Metals

chapter 28|15 pages

Insecticides

chapter 29|10 pages

Herbicides

chapter 30|11 pages

Rodenticides

chapter 33|11 pages

Radiation Toxicity