ABSTRACT

The term phytomedicine was coined by French physician Henri Leclerc in 1913. Till recently phytomedicine has remained in the background. But due to emerging challenges to the conventional pharmaceutical industry (cost effectiveness and potency of the drugs), phytomedicine has made a dramatic comeback. Phytomedicine has witnessed several changes and several new concepts have been introduced. Phytomedicine, although, a separate discipline, is strongly linked to Phytotherapy and Phytopharmacology.

As the title suggests the book is an attempt to bridge the gap between fundamental and emerging concepts in this field of medicine. The book has been divided into two parts.

Part A deals with core issues of the phyto-pharmaceutical drug industry. The book begins with an introductory chapter dealing with basic definitions with phytomedicine. Chapters 2-5 narrate emerging subjects such as Phytopharmacovigilance, Phytopharmacoeconomics, Phytopharmacoepidemiology and Phytopharmacogenomics. Chapter 6 discusses ethical issues in phytomedicine. Chapter 7 covers recent advances in drug delivery systems in phytomedicine whereas Chapter 8 is about application of nanotechnology in the field of phytomedicine. The further chapters cover metabolomics, regulatory and legal aspects of the phyto-pharmaceutical drug industry. The chapter on herbal bioavailability enhancing agents is the salient feature of Part-A.

Part B is related to applied research in the field of phytomedicine. Experimental findings on phyto-bioactive agents such as withanolides, steroidal alkaloids, phytosteroids and phytocannabinoids have been elaborated.

Nine annexures related to herbal drug registration are included.

part A|81 pages

Industrial Aspects of Phytomedicine

chapter 1|10 pages

Introduction to Phytomedicine

chapter 2|5 pages

Phytopharmacovigilance

chapter 3|3 pages

Phytopharmacoeconomics

chapter 4|4 pages

Phytopharmacoepidemiology

chapter 5|3 pages

Phytopharmacogenomics

chapter 6|3 pages

Ethics in Phytomedicine

chapter 7|12 pages

Herbosomes

chapter 8|5 pages

Nanophytomedicine

chapter 9|4 pages

Metabolomics and Phytomedicine

chapter 10|6 pages

Clinical Research in Ayurveda

chapter 11|3 pages

Excepients for Phytodrugs

chapter 12|2 pages

Certifications for Phytodrug Industry

chapter 15|3 pages

Comfrey Based Herbal Products

chapter 16|5 pages

Herbal Bioenhancers

part B|227 pages

Bioactives from Phytomedicine

chapter 17|12 pages

Phytosteroids and Related Compounds

chapter 21|26 pages

Steroidal Alkaloids

chapter 22|11 pages

Guggulsterones

chapter 23|5 pages

Phytoecdysteroids

chapter 24|14 pages

Botany of Withanolides containing Herbs

chapter 25|6 pages

Anticancer Pharmacology ofWithaferin A

chapter 26|7 pages

Pharmacology of Withanolide A

chapter 27|3 pages

Pharmacology of Withanone

chapter 28|2 pages

Pharmacology of Withanolide D

chapter 29|18 pages

Miscellaneous Withanolides

chapter 30|3 pages

Sitoindosides

chapter 31|41 pages

Pyrrolizidine Alkaloids

chapter 32|16 pages

The Phytocannabinoids

chapter |32 pages

Annexures