ABSTRACT
Exome and genome sequencing are revolutionizing medical research and diagnostics, but the computational analysis of the data has become an extremely heterogeneous and often challenging area of bioinformatics. Computational Exome and Genome Analysis provides a practical introduction to all of the major areas in the field, enabling readers to develop a comprehensive understanding of the sequencing process and the entire computational analysis pipeline.
TABLE OF CONTENTS
part |53 pages
Introduction
part |38 pages
Raw Data Processing
part |67 pages
Alignment
part |133 pages
Variant Calling
part |51 pages
Variant Filtering
part |70 pages
Prioritization
part |82 pages
Cancer