ABSTRACT

Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors' collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various stati

chapter 1|28 pages

Introduction to Clinical Trials

chapter 2|46 pages

Defining the Question

chapter 3|40 pages

Study Design

chapter 4|26 pages

Sample Size

chapter 5|30 pages

Randomization

chapter 6|30 pages

Data Collection and Quality Control

chapter 7|30 pages

Survival Analysis

chapter 8|36 pages

Longitudinal Data

chapter 9|22 pages

Quality of Life

chapter 10|50 pages

Data Monitoring and Interim Analysis

chapter 11|38 pages

Selected Issues in the Analysis

chapter 12|16 pages

Closeout and Reporting