ABSTRACT

Nonsense-Mediated mRNA Decay is the first book devoted to nonsense-mediated mRNA decay (NMD). The rationale for such a book is the enormous information that studies of NMD have provided on the intricacies of post-transcriptional gene expression. The first five sections of the book are divided according to organism and begin with chapters on S. cere

part |2 pages

Section II: Mammals

chapter 4|14 pages

NMD in Mammalian Cells: A History

chapter 5|12 pages

Human Upf Proteins in NMD

chapter 6|14 pages

NMD and the Immune System

chapter 9|10 pages

NMD and Human Disease

chapter 10|16 pages

Therapies of Nonsense-Associated Diseases

part |2 pages

Section III: Caenorhabditis elegans

chapter 11|12 pages

NMD in Caenorhabditis elegans

part |2 pages

Section IV: Drosophila melanogaster

part |2 pages

Section V: Plants

chapter 13|6 pages

NMD in Plants

part |2 pages

Section VI: Evolutionary Aspects of NMD

part |2 pages

Section VII: Roles for NMD Factors Other Than in NMD