ABSTRACT
Currently, isotretinoin is the drug of choice for the management of severe,
treatment-resistant acne vulgaris. Treatment with isotretinoin can lead to both
marked improvement and long-lasting remission. Essentially, isotretinoin has the
capacity to “cure” acne. In a field where physicians are usually resigned to
suppressing inflammatory skin disorders until they “burn out,” this power of
isotretinoin is astounding.
