ABSTRACT
Introduction 537
Clinical Study with EvelleR 538 Results 540
Discussion 541
References 543
INTRODUCTION
The skin protects our body from environmental harm, plays an important role in
controlling water retention and body temperature, and is an essential part of the
immune system. Further to the vital biological functions, the skin plays a pivotal
role in the feeling of well being and physical attractiveness, determined by color,
surface texture, and physiological properties such as elasticity, sweat, scent, and
sebum production (1). With increasing age, skin appearance gradually declines,
ultimately leading to reduction and coarsening of collagen, elastosis, wrinkling,
laxity, atrophy, irregular pigmentation, and dryness (2). Various environmental
factors are understood to accelerate this process: UV radiation, free radicals,
toxic and allergic compounds, immune and hormonal status, mechanical strain,
cigaret smoking, and stress.
