ABSTRACT
General principles The recognition of valvular heart disease can be challenging. The condition of the patient may range in severity from asymptomatic to severe distress. Moreover, the illness may not be readily attributable to the cardiovascular system. Infective endocarditis may mimic a rheumatologic or neurologic condition, while acute mitral regurgitation may be misinterpreted as a primary pulmonary disorder. Making a prompt and accurate diagnosis, while avoiding excessive laboratory investigation, may test the acumen of seasoned clinicians.
