ABSTRACT

Skin biopsy performed for the purpose of diagnosing blistering skin disease is an essential component of proper disease management. Depending on the purpose of a given biopsy, it can be obtained from lesional skin or from perilesional skin. In addition, the skin samples collected are placed in a different preserving medium or compound according to the type of tests for which they will be used. Careful consideration of the biopsy location and the preserving medium ensures the most efficient way of obtaining an accurate diagnosis.