ABSTRACT

Levodopa and apomorphine challenge tests may help to determine whether a patient is responsive to dopaminergic therapy (40).

Levodopa challenge: score the patient before and 60 min after a single high dose of levodopa (e.g. 250 mg). (Levodopa is given in the usual way in conjunction with a dopa-decarboxylase inhibitor, as Sinemet (co-careldopa) or Madopar (cobeneldopa), in a standard-release formulation).