ABSTRACT

Wilm’s tumor (nephroblastoma) The peak age incidence for this tumor is 2 years, but onset from age 1-10 years is not unusual (220). The overall incidence world-wide is about 5 per million children under the age of 15 years. Presenting features include a visible/palpable mass, hematuria, and weight loss (or failure to grow). Surgery to remove the tumor is the definitive treatment. The tumor is usually large by the time it presents and has a pale firm cut surface (with islands of darker hemorrhage and necrosis). There is an immature spindle-cell stroma which surrounds primitive tubular and glomerular structures on micro-

therapy are extremely important adjunctive therapies. The cure rate in specialized centers is currently 80-90%.