ABSTRACT
Acute human immunodeficiency virus (HIV) infection, also known as acute retroviral syndrome and seroconversion illness, is the period from the initial infection with HIV to complete seroconversion. HIV primarily infects CD4+ T-lymphocytes and, soon after primary infection, the virus rapidly concentrates in lymphoid tissue. Most adults and adolescents infected with HIV remain symptom free for long periods although viral replication continues to occur at a high pace. The diagnosis of primary HIV infection is usually made by documentation of HIV seroconversion, the development of anti-HIV antibodies, with the enzyme linked immunosorbent assay technique confirmed by Western blot assays. Molluscum contagiosum (MC) is a viral infection almost universally encountered in sexually active individuals with HIV. Immunocompromised patients may present with atypical features of MC including unusual morphology and growth patterns. Diagnosis of genital MC is generally made by clinical examination of the patient. Diagnosis of oral hairy leukoplakia is usually straightforward in HIV-positive patients with characteristic clinical presentations.
