ABSTRACT
The introduction of regulatory criteria for transdermal drug delivery (TDD) has drawn attention to the effects of anatomical site on TDD. Understanding the factors that affect site-to-site variation in TDD could enable enhanced drug delivery and offer flexibility to use multiple application sites, allowing greater patient acceptance and compliance and reducing drug absorption variability between and within individuals. This entry looks at the effects of application site on TDD in light of the current understanding of the mechanism of drug permeation.
