ABSTRACT

Glaucoma is a term used as a general reference for many syndromes which have in common the loss of nerve fibre tissue at the optic nerve head (ONH). The visual effects are progressive loss of visual field and acuity leading to eventual blindness in untreated cases. The concept is that raised pressure within the eye (intra-ocular pressure-IOP) damages the nerve fibres either by direct action or indirectly by compromising their blood supply, as raised IOP limits perfusion of blood in the sensitive region of the ONH.