ABSTRACT
This chapter provides that the themed presentation encourages quick, focused study and detailed answers aid comprehension and encourages familiarity with motor neurone disease with essential diagrams, colour images and sample MRIs. Patients with ALS display both upper and lower motor neurone signs. The patient in the scenario exhibits fasciculations, which is a lower motor neurone sign, and increased tone, which is an upper motor neurone sign. Riluzole has been proven to effectively lengthen survival rates by 2–3 months (by slowing down disease progression) when used for 18 months. It is a neuroprotective drug that inhibits the release of glutamate and blocks the effects of it on N-methyl-D-aspartate receptors, thereby preventing excito-toxicity-mediated damage to neurones.
