ABSTRACT

In recent decades, dendrimers — free-shaped synthetic macromolecules — have garnered a great deal of scientific interest because of their unique molecular nanostructure. Used in a variety of scientific applications, dendrimers are now widely regarded as a safer, more precise and more effective way to practice medicine.





This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, which is currently revolutionizing drug delivery techniques through the development of engineered nanodevices. Edited by Istvan J. Majoros and James R. Baker Jr, two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy or drug delivery research.

Targeted Drug Delivery in General, New Technology in Medicine. General Carriers for Drug Delivery. Poly(amidoamine) Dendrimer Synthesis and Characterization. Optical and Biophotonic Applications of Dendrimer Conjugate. Dendrimer Conjugates for Cancer Treatment. Biological Application of PAMAM Dendrimer Nanodevices in vitro and in vivo. Dendrimer-based Targeted Apoptosis Sensors for Medical Application. MRI Using Targeted Dendrimer Contrast Agents. Nanoparticle — Membrane Interactions: Mechanism for Enhanced Permeability. Computer Simulations of Dendrimers. Dendrimer-Entrapped and Dendrimer-Stabilized Metal Nanoparticles for Biomedical Applications.