ABSTRACT

Lausanne, CH-1015 Lausanne, Switzerland c Centre de Neurosciences Psychiatriques, Centre Hospitalier Universitaire Vaudois,

Département de Psychiatrie, Site de Cery, CH-1008 Prilly/Lausanne, Switzerland

pierre.marquet@chuv.ch and pierre.magistre@epfl.ch

Water represents up to 80% of the body mass; it is distributed evenly across

the intra-and extracellular compartments. Since the membranes of animal

cells are highly permeable to water [1], its movement across membranes is

in large part dictated by osmotic pressure gradients. Changes in extracellular

luid (ECF) osmolality cause water to low across cell membranes to

equilibrate the osmolality of the cytoplasm with that of the ECF.