ABSTRACT

The advent of nano-processing has led to the development of many

new technologies, a few of which are optical microscopy on the

nano-scale, optical near-field probes, single molecules as probes

for local fields, surface plasmonics, forces in confined fields and

others. Microwavemicroscopes formeasuring sub-wavelength sized

features embedded in a dielectric composite use a probe interacting

with the sample material via both evanescent and radiating fields

[1]. The optical properties of cavities are very sensitive to any

changes of the refractive index in their environment, making them

a promising solution for the detection of a number of important

viruses [2]. Optical forces can dominate in the tiny optical cavities

and they can provide a way of harnessing these forces, converting

them into micro-cavities that can mechanically adapt their geom-

etry [3]. Semiconductor quantum dots engineered to have both

fluorescent and paramagnetic properties offer great potential as

biological probes for imaging cellular activity. The probe is based on

a silica sphere incorporating the quantum dots with paramagnetic

nano-particles inside and target-specific groups attached to the

outside [4]. The ability to map the rheological characteristics

(mechanical properties such as elasticity and viscosity) of biological

tissues in vivo is important. A new optical method, Brillouin microscopy, with microscopic resolution is developed for this

purpose [5]. Optical antennas have the potential to become powerful

tools for nano-bio-imaging by enhancing the optical fields at this

miniature scale [6]. The development of optical trapping techniques

to control objects at the nano-scale is an important and challenging

endeavour [7]. Sound waves generated by light are the basis of

a sensitive medical imaging technique with applications to cancer

diagnosis and treatment [8]. It is suggested recently that nano-

particles of concentric structures with the cores made of ordinary

dielectrics and the shells of plasmonic materials, or vice versa, can

have resonant frequencies tuned by the ratio of the radii of the

core and the shell in a wide frequency range [9-11]. One of the

possible applications of the plasmonic materials is to build antenna

devices radiating and receiving electromagnetic energy at optical

frequencies – a very important concept for the construction of a

variety of probes. The high-Q factor, augmented sensitivity, and the

potential directional characteristics offered by the optical nano-

resonatorsmake them important components for chemical-and bio-

sensing applications.