ABSTRACT
The fabrication or synthesis of nanowires (NWs) has been studied intensively over the past decades. The unique physical properties of NWs and the ability to offer highly sensitive detection make NWbased biosensors a promising choice for next generation biosensors, especially for medical, food and environment applications. Deeper and thorough understanding on how to grow or fabricate NWs for biosensing purposes is crucial. This chapter discusses various techniques, either with bottom-up or top-down approaches, to synthesize or fabricate NWs. The advantages and disadvantages of bottom-up and top-down methods will also be discussed and weighted, thus providing an idea of the more suitable or promising techniques for making SiNW FETs (field effect transistor) as sensors. The importance of the field effect and doping concentrations inside
Thomas Moh Shan Yau,a,b,* Gregory Pandraud,a Louis C.P.M. de Smet,b Ernst J.R. Sudhölter,b Cees J.M. van Rijn,c and Pasqualina M. Sarroa Delft University of Technology, The Netherlands, a Delft Institute of Microsystems and Nanoelectronics, b Department of Chemical Engineering, Nano Organic Chemistry,c Nanosens, The Netherlands *t.s.y.moh@tudelft.nl
NWs for biosensing devices are summarized and compared. Finally, issues and future challenges related to SiNW FETs as biosensors will also be briefly discussed.
