ABSTRACT

Nowadays neutron and X-ray scattering methods are actively used for structure characterization of various types nanosystems in bulk and at interfaces. Small-angle neutron (SANS) and X-ray (SAXS) scattering are powerful methods for structure diagnostic of various objects within 1-100 nm length scale. In this review, the successful application of small-angle scattering is presented by examples of magnetic fluids, specific protein aggregates (amyloids) and the synthetic biological complex (magnetoferritin). The structure analysis of synthetic biological complex of magnetoferritin containing an iron oxide core inside a protein shell (apoferritin) in aqueous solutions as well as various types

of magnetic fluids for biomedical applications are reviewed. The combination of SANS, SAXS and atomic-force microscopy methods (applied to the samples prepared from the same initial solution) proved to be a rather effective approach to study various helical structures like amyloids fibrils.