ABSTRACT

In this last chapter, we will concentrate on fluorescence diffuse optical tomography (FDOT) used as the probe in deep biological tissue. A joint differential equation of FDOT (excitation and emission) can be reduced to a problem of two separate differential equations of diffuse optical tomography under the same assumptions. In FDOT, we use a fluorescent dye (e.g., indocyanine green) to increase tissue contrast between normal and disordered ones (e.g., breast cancer tissues). Fluorescence itself offers functional information about a tissue’s nature, such as oxygenation.