ABSTRACT

In Fourier domain (FD) optical coherence tomography (OCT), the

interference pattern is recorded as a function of light frequency

which can either be encoded spatially with the help of a diffraction

grating and a camera or be encoded in time using a sweeping

frequency laser source. FD-OCT systems typically have a sensitivity

advantage of about 20-30 dB over the conventional time domain

(TD) OCT systems [1, 2]. The sensitivity advantage of FD-OCT

and possibility to enhance imaging speed by parallelization has

motivated researchers to develop line field (LF) FD-OCT and

swept source (SS) full-field (FF) OCT imaging techniques. The

LF-FD-OCT setup typically consists of a Michelson interferometer

with an anamorphic illumination system using a broadband light

source to produce a line illumination on the sample and the

reference mirror. The light reflected from the sample and the

reference arm is combined and dispersed using a diffraction

grating, and subsequently detected by a 2D charge-coupled device

(CCD)/complementary metal-oxide semiconductor (CMOS) camera.

Thus, a spectrally resolved interference signal of each point on the

line illuminating the sample is obtained in parallel. A simple 1D

fast Fourier transformation (FFT) along the spectral dimension of

the data (after λ → k interpolation) yields an XZ cross-sectional image. A working LF-FD-OCT system was first demonstrated by

Zuluaga and Richard-Kortum using a technical sample [3]. This

technique has been further developed by Grajciar et al. [4] and

Nakamura et al. [5] for in vivo ophthalmic imaging. However, this

technique still requires scanning along one lateral direction in order

to acquire 3D volume image. On the other hand, SS-FF-OCT does

not require scanning of the sample in any direction. The FF-SS-

OCT setup usually consists of a free-space Michelson interferometer

and involves area illumination with a sweeping wavelength laser

source on the sample and the reference mirror. The detection of

the generated interference signal is performed by a high-speed 2D

camera. The 2D interference signal is recorded for each wavelength

sequentially in time, and 1D FFT (after λ → k interpolation) is performed along the spectral dimension to get a 3D volume image

with depth information of the sample.