ABSTRACT
Histological and immunohistochemical analyses of surgery samples
remain the current gold standard method used to analyze tumorous
tissue due to advantages of subcellular level resolution and high
contrast. However, these methods require lengthy (12 to 72 h),
complex multiple steps, and use of carcinogenic chemical products
that would not be technically possible intra-operatively. In addition,
the number of histological slides that can be reviewed and analyzed
by a pathologist is limited, and it defines the number and size of
sampled locations on the tumor, or the surrounding tissue.
