ABSTRACT
Liposomes, first described by British hematologist A.D. Bangham1-3 at the Babraham Institute, UK, in 1961, are artificially prepared spherical vesicles composed of phosphatidylcholine-enriched phospholipid bilayers. They can be categorized into multilamellar vesicles, small unilamellar vehicles, large unilamellar vesicles, and cochleate vesicles.4 Liposomes are formed spontaneously when amphipathic lipids are dispersed in an aqueous environment, and during the formation, they encapsulate a portion of the solution containing marker molecules (intended to be entrapped inside of liposome cavity) in which they were dispersed. Thereafter, liposomes have been regarded as models for artificial cells or
used as a vehicle for the delivery of pharmaceutical drugs and administration of nutrients.
