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Book

BRAIN SLICES in BASIC and CLINICAL RESEARCH

Book

BRAIN SLICES in BASIC and CLINICAL RESEARCH

DOI link for BRAIN SLICES in BASIC and CLINICAL RESEARCH

BRAIN SLICES in BASIC and CLINICAL RESEARCH book

BRAIN SLICES in BASIC and CLINICAL RESEARCH

DOI link for BRAIN SLICES in BASIC and CLINICAL RESEARCH

BRAIN SLICES in BASIC and CLINICAL RESEARCH book

ByAvital Schurr, Benjamin M. Rigor
Edition 1st Edition
First Published 1995
eBook Published 31 March 2020
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/9780367812157
Pages 352
eBook ISBN 9780367812157
Subjects Bioscience, Medicine, Dentistry, Nursing & Allied Health
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Schurr, A., & Rigor, B.M. (1995). BRAIN SLICES in BASIC and CLINICAL RESEARCH (1st ed.). CRC Press. https://doi.org/10.1201/9780367812157

ABSTRACT

Brain Slices in Basic and Clinical Research describes advancements in the field of brain function and dysfunction through use of central nervous system slice preparations. Topics are authored by leading scientists and include the following:

  • Mechanisms of synaptic plasticity as the basis of memory processes
  • Chaos and synaptic variability
  • Brain calcium currents
  • Glutamate receptors
  • Pathophysiology of excitotoxins
  • Cerebral hypoxia-ischemia
  • Neuronal injury
  • Free radicals
  • Optical methods of measuring brain metabolism
  • Voltammetry in brain slices
  • Calcium imaging
  • Patch-clamp recording and application of macromolecules through patch-clamp pipettes in brain slices
  • Intracellular double labeling of various neuronal populations
  • Use of brain slices in teaching neurophysiological methods
    Most of the topics are published in book format for the first time, and some of the techniques are more fully detailed than in any other book.
  • TABLE OF CONTENTS

    chapter Chapter 1|25 pages

    Advances in Understanding the Mechanisms Underlying Synaptic Plasticity

    ByTimothy J. Teyler, Idil Cavus, Chris Coussens, Pascal DiScenna, Lawrence Grover, Yi-Ping Lee, Zeb Little

    chapter Chapter 2|19 pages

    Chaotic Components of Synaptic Variability in Hippocampal Pathways

    ByPeter G. Aitken, Steven J. Schiff, Tim Sauer

    chapter Chapter 3|17 pages

    Intrinsic Optical Properties of Brain Slices: Useful Indices of Electrophysiology and Metabolism

    ByThomas J. Sick, Joseph C. LaManna

    chapter Chapter 4|24 pages

    Voltammetry in Brain Slices

    ByJonathan A. Stamford

    chapter Chapter 5|10 pages

    Imaging of Intracellular Calcium in Hippocampal Slices: Methods, Limitations, and Achievements

    ByMenahem Segal, Jonathan M. Auerbach

    chapter Chapter 6|18 pages

    Patch-Clamp Recording in Brain Slices

    ByFrances A. Edwards

    chapter Chapter 7|14 pages

    Intracellular Application of Macromolecules Through Patch Pipettes in Brain Slices

    ByMeenakshi Alreja, George K. Aghajanian

    chapter Chapter 8|18 pages

    Intracellular Double Labeling of Substantia Nigra and Pedunculopontine Neurons in in vitro Slice Preparation

    BySteve T. Kitai, Y. Kuga

    chapter Chapter 9|22 pages

    The Importance of Temperature Control When Investigating High Threshold Calcium Currents in Mammalian Neurones

    ByR. Hamish McAllister-Williams, John S. Kelly

    chapter Chapter 10|16 pages

    A Neurochemical Approach to Elucidate Metabotropic vs. Ionotropic Glutamate Receptor Activities in Rat Hippocampal Slices

    ByDarryle D. Schoepp, Manisha A. Desai

    chapter Chapter 11|34 pages

    Radiotracer Labeling of Brain Slices

    ByGeorge C. Newman, Frank E. Hospod, Clifford S. Patlak, Hui Qi

    chapter Chapter 12|21 pages

    The Pharmacology of Excitotoxins and Energy Deprivation in Hippocampal Slices

    ByAvital Schurr, Benjamin M. Rigor

    chapter Chapter 13|13 pages

    Delayed Neuronal Injury in the Hippocampal Slice

    ByRoi Ann Wallis, Kimberly L. Panizzon

    chapter Chapter 14|15 pages

    Gene Expression as an Index of Pathophysiology Associated with Slice Preparation

    ByThaddeus S. Nowak, Qihong Zhou, Pamela J. Voulalas, John M. Sarvey

    chapter Chapter 15|21 pages

    Studies on Anoxic Depolarization

    ByMaurizio Balestrino

    chapter Chapter 16|18 pages

    The Use of Brain Slices in the Study of Free Radical Actions

    ByTerry C. Pellmar

    chapter Chapter 17|9 pages

    Using the in vitro Hippocampal Slice as a Model to Teach Methods in Neurophysiology

    BySally Veregge
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