ABSTRACT
Similar to other biomolecules such as proteins and nucleic acids, glycans also had a rich history in therapeutic applications.4-6 However, due to their high complexity and structural diversity, glycans were omitted in the last century as DNA-and protein-focused treatments became readily accessible. Nevertheless, the recent development in carbohydrate synthesis and analysis fuelled the interest in glycan-based drug discovery.7 This chapter is mainly focused on two different aspects: (1) a brief description of carbohydrate-based drugs and vaccines currently available on the market for the treatment of various diseases and (2) the possibilities of sulfated marine carbohydrates in drug discovery.
