ABSTRACT

In the context of off ring assisted reproduction technology (ART), the three most commonly encountered infections are human immunodeficiency virus (HIV) types 1 and 2, hepatitis B virus (HBV), and hepatitis C virus (HCV). Less frequently encountered, but routinely screened for, is human T-lymphocyte virus 1 (HTLV-1) and HTLV-2. More recently, concerns have been raised over Zika virus. A total of 75% of individuals infected with HIV and HCV are in the reproductive age group and wish to both conceive safely and reduce viral transmission risk to their partner and offspring. Understanding viral transmission risk is paramount to tailoring an effective ART program for those with viral infections. Minimizing viral transmission risk differs according to whether couples are virus serodiscordant or concordant and whether viral load in the blood is detectable or not.