ABSTRACT

T HE EVOLUTION OF TECHNOLOGICAL ADVANCES in infrared sensor technology, image processing, “smart” algorithms, knowledge-based databases and their overall system integration has resulted in new methods of research and use in medical infrared imaging. The development

of infrared cameras with focal plane arrays not requiring cooling added a new dimension to this modality. New detector materials with improved thermal sensitivity are now available and production of highdensity focal plane arrays (640×480) have been achieved. Advance read-out circuitry using on-chip signal

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processing is in common use. These breakthroughs permit low-cost and easy-to-use camera systems with thermal sensitivity less than 50 milli-kelvin degrees, as well as spatial resolution of 25 to 50 µm, given the appropriate optics. Another important factor is the emerging interest in the development of smart image processing algorithms to enhance the interpretation of thermal signatures. In the clinical area, new research addresses the key issues of diagnostic sensitivity and specificity of infrared imaging. Efforts are underway to achieve quantitative clinical data interpretation in standardized diagnostic procedures. For this purpose, clinical protocols are emphasized.