ABSTRACT
This chapter outlines the effects on the immune system that have been observed when animal and human subjects have been exposed to aerosolized jet fuels. Chronic jet fuel exposure could be detrimental to the health and well-being of exposed personnel, adversely affect their work performance, and predispose these individuals to increased incidences of infectious disease, cancer, and autoimmune disorders. Exposure to environmental toxicants may have significant effects on the immune system. An in-depth analysis of the effects of Jet Propulsion Fuel-8 (JP-8) exposure on specific components of the cellular immune system was performed. Similar results have now been obtained when using a novel jet fuel exposure system based on real-time, in-line analysis of both aerosol and vapor-phase JP-8 concentrations during the exposure protocol. A discussion of potential real-world consequences of such exposure and effects is discussed, as well as methods by which to ameliorate the effects of jet fuel exposure.
