ABSTRACT
It has been more than a decade since the introduction of the combined positron emission tomography and computed tomography (PET/CT) [1,2], which has been well recognized as the most sensitive tool for detecting neoplasm. The PET/CT technology, including detectors, reconstruction algorithms, and image analysis, matures over the years while researchers are still striving for better image quality and quantitation with lower radiation dose. To achieve this goal, various imaging degradation factors need to be compensated and we mainly focus on attenuation and respiratory motion blurring in this chapter.
