ABSTRACT
I. Introduction The goal of tuberculosis (TB) control programs is to cure patientswith disease due to infection with Mycobacterium tuberculosis, in order to avert deaths, prevent the development of new cases, and prevent the emergence of drug resistance. Nevertheless, drug-resistant TB (DR-TB) is bound to appear in even the best-run programs. There is considerable evidence that drug resistance has emerged and is on the upsurge in many parts of the world (1). This chapter focuses on the care of patients with DR-TB and examines the origins, prevention, diagnosis, and impact of drug resistance on TB control.
