ABSTRACT

Arousal ........................................................................................................ 243 9.4.1 Lesions ............................................................................................244 9.4.2 Systemically Administered Pharmacological Manipulations .........244 9.4.3 Intratissue Infusions of Drugs to Identify Sites of Action .............245 9.4.4 Neurochemical Measures of Stimulant-Induced Alterations in Rates of

Neurotransmitter Release.................................................................246 9.5 Procedures for Assessment of the Arousal-Enhancing Actions of

Pharmacological Treatments .......................................................................247 9.5.1 EEG-Modulating Actions of Pharmacological Manipulations in

Halothane-Anesthetized Animals ...................................................247 9.5.2 EEG/EMG-Based Assessment of Time Spent in Sleep-Wake

States ...............................................................................................249 9.5.3 Behavior-Based Assessment of Time Spent in Sleep-Wake

States ...............................................................................................250 9.5.4 Assessment of the Wake-Promoting Actions of Intracerebral

Infusions ..........................................................................................251