ABSTRACT

In the ELINK (EU Workshop on Linking Aquatic Exposure and Effects in the Registration Procedure of Plant Protection Products) decision scheme (Figure 2.1), the higher-tier risk assessment procedures mentioned in Box 4 refer to toxicokinetic and toxicodynamic (TK/TD) modeling approaches. This chapter aims 1) to shed light on the current state of the art of TK/TD modeling and 2) to describe how TK/TD models can be used in the risk assessment for pesticides. Although some

7.1 Introduction ....................................................................................................85 7.2 TK/TD Models Available ...............................................................................86