ABSTRACT

Nutrient-gene interaction The Human Genome Project found that a human has about 25,000 genes. Not all genes are expressed in all cells at all times. Conditional expression of genes implies existence of controls that determine when codes are transcribed and translated into gene products. Metabolic control mechanisms involve hormones, metabolites, ions, and second messengers that modify the individual’s (phenotypic) expression of these genes. These control mechanisms may be metabolic products of biochemical reactions, nutrients, or both.