ABSTRACT
PPI networks can be modeled by graphs where nodes represent proteins and edges show the interactions between them. These networks act as an interface between the genome and the metabolism as shown in Figure 10.1. They perform the functions under the control of the genes which results in biochemical reactions governing metabolism. Using technologies such as mass spectrometry provided large volumes of data of PPI networks; however, the size of data and the fact that it contains significant noise make the analysis difficult.
