ABSTRACT

Traditionally surgical curettage has been performed following the diagnosis of miscarriage, on the assumption that this prevents haemorrhage and decreases the risk of subsequent gynaecological infection. Medical management of miscarriage has been increasingly used as an alternative to surgical management for the past 10 years. Treatment regimens include the use of the antiprogesterone, mifepristone and a prostaglandin analogue, the most commonly used of which is misoprostol (15-deoxy,16-hydroxy,16-methyl analogue of prostaglandin E1). The aim of this chapter is to review the evidence for both medical and surgical management and consider the risks, benefits and practicability of these management options.

MEDICAL MANAGEMENT