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Book

The COST Manual of Laboratory Animal Care and Use

Book

The COST Manual of Laboratory Animal Care and Use

DOI link for The COST Manual of Laboratory Animal Care and Use

The COST Manual of Laboratory Animal Care and Use book

Refinement, Reduction, and Research

The COST Manual of Laboratory Animal Care and Use

DOI link for The COST Manual of Laboratory Animal Care and Use

The COST Manual of Laboratory Animal Care and Use book

Refinement, Reduction, and Research
Edited ByBryan Howard, Timo Nevalainen, Gemma Perretta
Edition 1st Edition
First Published 2010
eBook Published 18 October 2010
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/b13591
Pages 439
eBook ISBN 9780429146060
Subjects Bioscience, Environment & Agriculture
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Howard, B., Nevalainen, T., & Perretta, G. (Eds.). (2011). The COST Manual of Laboratory Animal Care and Use: Refinement, Reduction, and Research (1st ed.). CRC Press. https://doi.org/10.1201/b13591

ABSTRACT

COST (European Cooperation in the field of Scientific and Technical Research) is an intergovernmental initiative in science and research intended to promote the coordination of nationally funded research in Europe. Four working groups discuss the housing of animals, their environmental needs, refinement of procedures, genetically modified animals, and cost-benefit analysis. Based on the activities of these working groups, this book provides the European best practices for individuals and institutions working with laboratory animals. The text also discusses the ethical evaluation of experiments and procedures involving animals.

TABLE OF CONTENTS

chapter 1|5 pages

Introduction

ByBryan Howard

Size: 0.10 MB

chapter 2|21 pages

Design and Oversight of Laboratory Animal Facilities

ByDag Sørensen, Heinz Brandstetter, Nikolaos Kostomitsopoulos, Richard Fosse

Size: 0.67 MB

chapter 3|45 pages

Housing and Care of Laboratory Animals

ByHanna-Marja Voipio, Ping-Ping Tsai, Heinz Brandstetter, Marcel Gyger, Hansjoachim Hackbarth, Axel Kornerup Hansen, Thomas Krohn

Size: 3.19 MB

chapter 4|26 pages

Animal Needs and Environmental Refinement

ByVera Baumans, Hanna Augustsson, Gemma Perretta

Size: 1.31 MB

chapter 5|29 pages

Ethical Evaluation of Scientific Procedures: Recommendations for Ethics Committees

ByRony Kalman, I. Anna S. Olsson, Claudio Bernardi, Frank van den Brook, Aurora Brønstad, Istran Gyertyan, Aavo Lang, Katerina Marinou, Walter Zeller

Size: 0.28 MB

chapter 6|19 pages

Reduction by Careful Design and Statistical Analysis

ByMichael Festing

Size: 0.33 MB

chapter 7|28 pages

Animal Models: Selecting and Preparing Animals for a Study

ByPatrick Hardy, Sarah Wolfensohn

Size: 0.28 MB

chapter 8|26 pages

Creation of Genetically Modified Animals

ByBelen Pintado, Marian van Roon

Size: 1.81 MB

chapter 9|22 pages

Management of Genetically Modified Rodents

ByJan-Bas Prins

Size: 0.23 MB

chapter 10|29 pages

Impact of Handling, Radiotelemetry, and Food Restriction

ByTimo Nevalainen, Marlies Leenaars, Vladiana Crljen, Lars Friis Mikkelsen, Ismene Dontas, Bart Savenije, Carlijn Hooijmans, Merel Ritskes-Hoitinga

Size: 2.00 MB

chapter 11|29 pages

Basic Procedures: Dosing, Sampling and Immunisation

ByIsmene Dontas, Jann Hau, Katerina Marinou, Timo Nevalainen

Size: 0.44 MB

chapter 12|25 pages

Imaging Techniques

ByAurora Brønstad, Ismene Dontas

Size: 4.40 MB

chapter 13|20 pages

Anaesthesia and Analgesia

ByPatricia Hedenqvist, Paul Flecknell

Size: 0.20 MB

chapter 14|21 pages

Use of Humane Endpoints to Minimise Suffering

ByCoenraad Hendriksen, David Morton, Klaus Cussler

Size: 0.91 MB

chapter 15|14 pages

Euthanasia

ByLuis Antunes

Size: 0.18 MB

chapter 16|22 pages

Education, Training, and Competence

ByBryan Howard, Katey Howard, Peter Sandøe

Size: 0.24 MB

chapter 17|13 pages

Animal Experimentation and Open Communication

ByAnn-Christine Eklöf, Anne-Grethe Berg, Jon Richmond

Size: 0.17 MB
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