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Cytolytic Lymphocytes and Complement: Effectors of the Immune System

Book

Cytolytic Lymphocytes and Complement: Effectors of the Immune System

DOI link for Cytolytic Lymphocytes and Complement: Effectors of the Immune System

Cytolytic Lymphocytes and Complement: Effectors of the Immune System book

Volume 2

Cytolytic Lymphocytes and Complement: Effectors of the Immune System

DOI link for Cytolytic Lymphocytes and Complement: Effectors of the Immune System

Cytolytic Lymphocytes and Complement: Effectors of the Immune System book

Volume 2
Edited ByEckhard R. Podack
Edition 1st Edition
First Published 1988
eBook Published 22 December 2017
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/9781351071291
Pages 229
eBook ISBN 9781351071291
Subjects Environment & Agriculture
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Podack, E.R. (Ed.). (1988). Cytolytic Lymphocytes and Complement: Effectors of the Immune System: Volume 2 (1st ed.). CRC Press. https://doi.org/10.1201/9781351071291

ABSTRACT

These volumes, Cytolytic Lymphocytes and Complement: Effectors of the Immune System, originate from the realization that pathways of recognition and killings of foreign targets follow similar routes in the humoral and cellular part of the immune system. In particular, the homology of immunoglobins with the T-cell-MHC-antigen receptor at the beginning of the recognition sequence and the homology of complement component C9 with lymphocyte perforin 1 (P1) as pore formers at the end of the effector sequence are striking examples.

TABLE OF CONTENTS

part II.B|58 pages

Cytolytic Mechanism — Killer Lymphocytes

chapter 15|16 pages

Properties and Function of Cytolytic Lymphocyte Granules

ByEckhard R. Podack

chapter 16|16 pages

Properties of Transmembrane Channels Induced by Cytolytic Lymphocytes

ByJohn Ding-E Young, Eckhard R. Podack, Carl F. Nathan, Hans Hengartner, Zanvil A. Cohn

chapter 17|24 pages

The Role of Nuclear Damage in Lysis of Target Cells by Cytotoxic T Lymphocytes

ByRichard C. Duke, J. John Cohen

part II.C|74 pages

Cytolytic Mechanism — Soluble Cytotoxic Factors Produced by Lymphocytes

chapter 18|14 pages

Production and Function of Lymphotoxin Secreted by Cytolytic T Cells

ByDonald Scott Schmid, Nancy H. Ruddle

chapter 19|16 pages

Tumor Necrosis Factor/Cachectin

ByFrederick C. Kull

chapter 20|14 pages

Natural Killer Cytotoxic Factor (Nkcf) as Mediator in the Lytic Pathway of Nk Cell Mediated Cytotoxicity*

ByBenjamin Bonavida, Susan C. Wright

chapter 21|28 pages

Tumor Necrosis Factors

ByRamani A. Aiyer, Bharat B. Aggarwal

part III|74 pages

Therapeutic Applications

chapter 23|8 pages

A Function for Nk Cells in Acute Bone Marrow Allograft Rejection*

ByGunther Dennert

chapter 24|14 pages

Cytolytic T Lymphocyte Clones in Anti-Viral Immunity: Effector Function in Vivo and Mechanism of Action *

ByT. J. Braciale, A. E. Lukacher, М. T. Sweetser, V. L. Braciale

chapter 25|18 pages

Interleukin-2 Activated Cytotoxic Lymphocytes (Lak Cells) as Antigen Nonspecific Amplifiers of the Immune Response: General Characteristics and Considerations For Cancer Therapy

ByElizabeth Ann Grimm

chapter 26|12 pages

The Contribution of Natural Killer and T-Cells to the Lymphokine-Activated Killer Cell Phenomenon

ByJoseph H. Phillips, Brett T. Gemlo, Warren W. Myers, Anthony A. Rayner, Lewis L. Lanier

chapter 27|14 pages

Targeting for T-Lymphocyte-Mediated Lysis by Hybrid Antibodies

ByUwe D. Staerz, Leo Lefrancois, Michael J. Bevan

chapter 28|6 pages

Long-Term Growth and Expansion of Ril-2 Activated Nk- Cells for Cancer Therapy

ByEckhard R. Podack, Kristin O. Penichet, Ben-Yao Lin, Jen Wei Chiao, Abraham Mittelman
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