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Dermal Absorption and Toxicity Assessment

Book

Dermal Absorption and Toxicity Assessment

DOI link for Dermal Absorption and Toxicity Assessment

Dermal Absorption and Toxicity Assessment book

Dermal Absorption and Toxicity Assessment

DOI link for Dermal Absorption and Toxicity Assessment

Dermal Absorption and Toxicity Assessment book

Edited ByMichael S. Roberts
Edition 2nd Edition
First Published 2008
eBook Published 8 February 2013
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.3109/9780849375927
Pages 704
eBook ISBN 9780429131998
Subjects Bioscience, Medicine, Dentistry, Nursing & Allied Health
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Roberts, M.S. (Ed.). (2008). Dermal Absorption and Toxicity Assessment (2nd ed.). CRC Press. https://doi.org/10.3109/9780849375927

ABSTRACT

The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin ab

TABLE OF CONTENTS

chapter 1|16 pages

Human Skin Morphology and Dermal Absorption

chapter 2|20 pages

Animal Skin Morphology and Dermal Absorption

chapter 3|32 pages

The Physical Structure of the Skin Barrier

chapter 4|10 pages

Morphology of Epidermal Lipids

chapter 5|10 pages

Stratum Corneum as a Biosensor

chapter 6|28 pages

Cutaneous Metabolism

chapter 7|18 pages

Formulation Issues

chapter 8|6 pages

Interpretation of In Vitro Skin Absorption Studies of Lipophilic Chemicals

chapter 9|20 pages

Use of Skin Equivalents for Dermal Absorption and Toxicity

chapter 10|18 pages

Skin Absorption as Studied by Spectroscopic Methods

chapter 11|30 pages

Physiologically Based Pharmacokinetics and Pharmacodynamics of Skin

chapter 12|42 pages

Beyond Stratum Corneum

chapter 13|20 pages

Biophysical Models for Skin Transport and Absorption

chapter 14|16 pages

Mathematical Models for Different Exposure Conditions

chapter 15|12 pages

Modeling Skin Permeability in Risk Assessment

chapter 16|10 pages

In Vitro–In Vivo Correlations in Transdermal Drug Delivery

chapter 17|14 pages

Estimation of Subsequent Systemic Exposure—Physiological Models

chapter 18|16 pages

RISKOFDERM: Predictions Based on In Vivo Factors

chapter 19|20 pages

Quantitative Structure–Activity Relationships for Skin Corrosivity and Sensitization

chapter 20|12 pages

Allergic Contact Dermatitis

chapter 21|20 pages

Irritancy of Topical Chemicals in Transdermal Drug Delivery Systems

chapter 22|14 pages

Photosensitivity Induced by Exogenous Agents: Phototoxicity and Photoallergy

chapter 23|28 pages

Systemic Toxicity Caused by Absorption of Drugs and Chemicals Through Skin

chapter 24|16 pages

Solvent and Vehicle Effects on the Skin

chapter 25|10 pages

United States Environmental Protection Agency Perspectives on Skin Absorption and Exposure

chapter 26|12 pages

Dermal Absorption of Chemicals: Some Australian Regulatory Considerations

chapter 27|12 pages

International Perspectives in Dermal Absorption

chapter 28|12 pages

Structure–Activity Relationships and Prediction of Photoallergic and Phototoxic Potential

chapter 29|12 pages

Potential Regulatory Use of (Q)SARs to Develop Dermal Irritation and Corrosion Assessment Strategies

chapter 30|16 pages

Development of (Q)SARs for Dermal Irritation and Corrosion Assessment Using European Union New Chemicals Notification Data

chapter 31|14 pages

Regulatory Assessment of Skin Sensitization

chapter 32|12 pages

Assessment of Topical Bioequivalence Using Microdialysis and Other Techniques

chapter 33|14 pages

An Industry Perspective of Topical Dermal Bioequivalence

chapter 34|12 pages

Dermal Absorption of Chemical Contaminants from Soil

chapter 35|18 pages

Percutaneous Absorption of Pesticides

chapter 36|12 pages

Bathing Water: Percutaneous Absorption of Water Contaminants

chapter 37|18 pages

Percutaneous Absorption of Prodrugs and Soft Drugs

chapter 38|12 pages

Skin Penetration of Cosmetic Ingredients and Contaminants

chapter 39|16 pages

Percutaneous Absorption of Hair Dyes

chapter 40|14 pages

Dermal Absorption of Fragrance Materials

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