ABSTRACT
Over 80% of multiple sclerosis (MS) patients have symptoms of lower genitourinary tract dysfunction. More than 96% of patients with the disease for 10 years will have had urological manifestations1-6. The effects of MS on the genitourinary tract can range from bladder and urethral dysfunction to impotence. Consequently, genitourinary symptoms can be a source of considerable frustration and distress for the patient with MS. Urological involvement presents most commonly as either lower urinary tract (bladder and urethral) dysfunction (LUTD) or sexual dysfunction. Because LUTD and sexual dysfunction can have a significant impact on patient quality of life, a working knowledge of the pathophysiology, evaluation and treatment of these conditions is essential for the MS specialist who is often called upon to manage these severe, debilitating symptoms.
