ABSTRACT
There is growing interest in the pronounced variability in the incidence and severity of chronic respiratory diseases such as Asthma, observed to occur in any particular patient over a given period of time. It is now known that acute exacerbations are multi-factorial in origin, with pollution, allergens and viruses all implicated, and effective treatment requires a similarly complex approach that addresses each of the component causes. In this new volume, leading authorities review what is known of these causative factors and the mechanisms by which they exacerbate the symptoms of pulmonary disease both singly and in combination. The authors evaluate the individual efficacy of current treatments in the light of this knowledge and present new recommendations for formulating effective therapeutic regimens.
Short Contents
TABLE OF CONTENTS
part |2 pages
PART I Epidemiology
chapter 2|26 pages
Definition of acute asthma exacerbations in adults and children: differentiating asthma exacerbations from poor asthma control
chapter 6|22 pages
Etiology of asthma exacerbations in adults: differences from children
chapter 7|14 pages
Modes of transmission of respiratory viral infections
part |2 pages
PART II Pathophysiology
chapter 11|16 pages
Pathophysiology. Lessons from human respiratory syncytial virus bronchiolitis and acute wheezing episodes in infants
part |2 pages
PART III In vitro experimental models of asthma exacerbations
chapter 13|20 pages
In vitro models of macrophage infection
part |2 pages
PART IV In vivo experimental models of asthma exacerbations
part |2 pages
PART V Treatment and prevention of asthma exacerbations
part |2 pages
PART VI Delivery of care