ABSTRACT

Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic disease usually resulting from human chorionic gonadotropin (hCG) stimula­ tion of ovarian granulosa cells in gonadotropinstimulated ovaries. The syndrome exists in a clinical spectrum, with some patients exhibiting only mild disease, and other patients requiring intensive management. OHSS and the complica­ tions thereof have even resulted in reported fatalities1-5. In a widely used classification scheme, Navot et al. defined severe and critical forms of OHSS to help researchers and clini­ cians identify these serious and life-threatening conditions6. Clinicians managing patients with OHSS must be familiar with the syndrome and its diverse manifestations, and above all must be familiar with medical and surgical options in the treatment of the critically ill OHSS patient.