ABSTRACT
In the context of the cross-talk between the neuroendocrine and immune systems, increasing evidence shows that the physiology of the thymus is modulated by hormones and neuropeptides. Herein, we discuss examples of such control in terms of neuroendocrine influence upon distinct cell types of the organ. Before discussing these data, it is worthwhile to briefly comment on the process of intrathymic T-cell differentiation in the context of the thymic microenvironment.
