ABSTRACT

ABSTRACT: Neutrophil granulocytes play an important role in the human immune defense. One of their weapons against pathogens is the release of Neutrophil Extracellular Traps (NETs) which can form a biofilm. Biofilms can be detected by electrical impedance spectroscopy (EIS) and enables researchers to observe NET-formation, determine the reaction parameters and to investigate diseases. In this work we present how we adapted the measurement technique to this biological phenomenon and how we obtained first signs of a time-dependent behaviour for this reaction. We found significant changes in the impedance spectra depending on the stimulus. Different stimuli were also part of the study.