ABSTRACT
Background Lymphoma was initially described by Thomas Hodgkin in 1832. It includes Hodgkin’s disease (HD) and non-Hodgkin’s lymphoma (NHL), and is characterized by transformations of normal lymphoid cells at different stages of their development. Lymphoma may present as the involvement of one or more lymph node groups or of an isolated organ, or as widely disseminated disease. In general, enlarged lymph nodes displace other structures, but large-cell high-grade NHL may also be locally invasive.
