ABSTRACT
Clinically, the skin becomes relatively atrophic, lax, and wrinkled. Histologically, the epidermis becomes atrophic. Dermal features include decreased thickness, loss of elastic fibers, and a decrease in the biosynthetic capacity of fibroblasts1. The immune, endocrine, and neural functions of the skin also decrease with age. All these changes are genetically determined, and are therefore different in each individual.
