ABSTRACT
Pain is due to disease or treatment. The pain profile is unique to the disease. There are significant psychological and social consequences of disease which have a bearing on the pain syndrome, complex medication of antiretroviral therapy and treatment and prophylaxis for opportunistic infections and cancers. Sufferers may be substance abusers, which adds further complexity to the management of the condition. Patients are at increased risk of infection and neoplastic disorders and this should be borne in mind when providing symptomatic treatment.
