ABSTRACT

The endometrium of humans and some primates undergoes cyclical processes of regeneration, differentiation, and shedding as part of the menstrual cycle. Endometrial regeneration also follows parturition, almost complete curettage, and in postmenopausal women taking estrogen replacement therapy. Although physical shedding of endometrial tissue does not occur in non-menstruating species, there are cycles of endometrial growth and apoptosis.