ABSTRACT

The function of the extracellular matrix (ECM) can be broadly divided into two. First, it acts as a structural framework for tissue. The structural demands on endometrium change with pregnancy, and after parturition there is a need to return the ECM to its non-pregnant state.The hormonally controlled compositional and biomechanical changes in endometrial ECM during the reproductive cycle are some of the most rapid and extensive seen in adult physiology.